Does Semaglutide Make You Tired?
Feeling tired on semaglutide is common early in treatment or after dose increases. Learn why it happens, how long it lasts, and when to seek advice.
Fatigue or a feeling of tiredness can happen — especially during the first few weeks of treatment or during a dose increase. This is thought to be related to gastrointestinal changes and caloric intake changes as your appetite adjusts. Again, these feelings usually fade with continued use as your body acclimates.
If fatigue persists beyond a few weeks or is severe, discussing it with your provider is important — because persistent tiredness can sometimes be related to other nutritional changes or underlying conditions.
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